Healthcare technology company Semler Scientific is facing a significant setback from its Bitcoin investment strategy, reporting an unrealized loss of $41.8 million in the first quarter of 2025. The company’s holdings, which include 3,182 BTC valued at roughly $263.5 million, declined by 12% throughout the quarter, leading to a drop in value from around $93,500 in early January to $82,350 by March’s end. This downward trajectory continued into April, with Bitcoin briefly falling below $75,000—a 32% decrease from its peak. Despite these losses, Semler remains dedicated to accumulating Bitcoin, according to CEO Doug Murphy-Chutorian who stated the company is “laser-focused” on increasing its BTC holdings while pursuing growth in its healthcare business.