Ethereum Retakes DeFi Crown with $480B in Stablecoin Transactions

Ethereum has regained its position as the leader in the decentralized finance (DeFi) market, reaching a staggering $480 billion in stablecoin transactions during May 2025. This surge is largely driven by automated trading bots and a shift back to Ethereum’s mainnet from Layer 2 solutions. The increased activity on Ethereum’s mainnet has boosted its transaction volume significantly, resulting in a notable market cap growth. Key factors contributing to this revival include improved infrastructure, reduced fees, and the rising efficiency of automated trading bots. Notably, user migration from Layer 2 platforms like Optimism is observed as they lost over $700 million in stablecoin supply, signaling a return to Ethereum’s mainnet for many users.